منابع مشابه
The Side-chain Theory of the Structure
INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Direction and frequency of mutations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Origins and mutations of the genes of the bar series . . . . . . . . . . . . . . . . . . . . . . . Origins and mutations of the genes of the infrabar...
متن کاملProgress in the Side-Chain Prediction Problem
Structure prediction results from Rosseta@home at CASP7 [Das et al., 2007]
متن کاملExpert Antibody Side Chain Placement
Antibody modelling by side chain placement on an homologous backbone conformation is a combinatorially hard problem. This can be made tractable by using a knowledge-based approach in which a heuristic cost function is used to perform a structural search on a database of known structures in order to nd re-usable clusters of side chains. The procedure described yields a plausible structure which ...
متن کاملSynthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain
Utilization of benzoxazinone for synthesis quinazolinone derivatives with 3-heterocycle side chain. treatment of benzoxazinon 1 with cyano acetohydrazide or thionocarbohydrazide gave the quinazolinone derivatives 2 or 12. quinazolinone 2 has been utilized as synthon for new pyridinone, oxazet, thiazole, thiazolidinone and quinazolinone derivatives. Thiosemicarbazide and thiosemicarbazone deriv...
متن کاملA Short Method for the Synthesis of Alpha-Tocopherol Side Chain
The enzymatic hydrolysis of meso-1,7-diacetoxy-2,6-dimethylheptane 5, prepared from 2,6-dimethylhepta-1,6-diene 6, gave the (2S,6R)-7-acetoxy-2,6-dimethyl-1-heptanol 1, which was transformed to the (2R,6R)-2,6,10-trimethyl-1-undecanol 7. In this manner, the C14 side chain of a-Tocopherol was synthesized from 2,6-dimethylhepta-1,6-diene 6 in only 5 steps.
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2013
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2013.11.008